Spectrophotometric method for estimation of Valsartan in bulk and tablet dosage form

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ISSN: 2349-6002 ESTD Year: 2014

UGC approved journal no 47859

Spectrophotometric method for estimation of Valsartan in bulk and tablet dosage form
Author(s):
Dr.K.Sandhyarani, prof.K.Raghubabu
Keywords:
Valsartan, Eriochrome black-T and Spectrophotometric method
Abstract
Simple, accurate, rapid and sensitive method has been developed for the estimation of Valsartan in bulk and pharmaceutical formulations. The method is based on the formation of ion association complex of the drug with eriochrome black-T in acidic buffer of pH 3.5 followed by extraction into chloroform. The linearity range of Valsartan with eriochrome black-T was found to be 50 – 250 µg/mL. The developed method was found to be precise and accurate from the statistical validation of the analytical data. The proposed method has been successfully applied for analysis of dosage formulations.
Article Details
Unique Paper ID: 153201 Publication Volume & Issue: Volume 8, Issue 6 Page(s): 135 - 138
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