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@article{171448,
        author = {Shahzadi N Khan},
        title = {An Overview on Micronutrients Deficiency in Critical Condition - A review of Thalassaemia},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {7},
        pages = {3056-3059},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=171448},
        abstract = {Thalassemia is a hereditary disorder that disrupts normal hemoglobin synthesis, resulting in anemia and various systemic complications. Classified into two main types, alpha-thalassemia and beta-thalassemia, the disorder varies in severity based on the genetic mutation. Managing thalassemia involves blood transfusions, iron chelation therapy, and addressing micronutrient deficiencies, which collectively impose a substantial healthcare burden. This review highlights the critical role of micronutrients in managing thalassemia-related complications, emphasizing their importance in optimizing patient outcomes.
In this review, secondary data is collected and accordingly ascertain which micronutrient deficiency is common. Iron is a key component of hemoglobin and plays a crucial role in oxygen transport. Folic acid and vitamin B12 are essential for DNA synthesis and red blood cell production. Zinc and copper are involved in various enzymatic processes related to red blood cell development and function. Vitamin C enhances iron absorption, while antioxidants protect cells from damage caused by oxidative stress. Strategies for effective management include iron chelation therapy, tailored nutritional counseling, and regular monitoring of micronutrient levels. Emphasis is placed on a balanced diet rich in essential nutrients to mitigate oxidative stress, support red blood cell production, and improve patient outcomes.},
        keywords = {Chelation, haemoglobin, micronutrients, thalassaemia, and transfusion},
        month = {December},
        }