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@article{194274,
        author = {Poonam Namdeo Tidke and Mrs. Sheetal Umrajkar and Vaishnavi Sitaram Mohite},
        title = {Pyridine Derivatives as Antihypertensive Agents: A Review},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {10},
        pages = {3344-3352},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=194274},
        abstract = {Hypertension is a major cardiovascular disorder and a leading risk factor for morbidity and mortality worldwide. Despite the availability of several classes of antihypertensive drugs, there remains a need for agents with improved efficacy, safety, and patient compliance. Heterocyclic compounds, particularly pyridine and its derivatives, have attracted considerable interest due to their diverse pharmacological activities. Several clinically successful antihypertensive drugs, including calcium channel blockers and central sympatholytic, contain a pyridine nucleus. This review highlights the chemical significance of pyridine, its role in antihypertensive drug design, mechanisms of action, structure activity relationships (SAR), and clinically important pyridine- based antihypertensive agents, along with future perspectives in this field.},
        keywords = {Pyridine, Antihypertensive agents, Calcium channel blockers, SAR, Heterocyclic compounds},
        month = {March},
        }