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@article{197042,
        author = {shelja and Basanti Brar},
        title = {Comparative Analysis Among MSSA and MRSA: Association with Demographic Factors and Mannitol Fermentation Characteristics},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {11},
        pages = {6744-6751},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=197042},
        abstract = {Staphylococcus aureus is a pathogen of clinical significance that causes a broad range of infections, and the appearance of methicillin-resistant strains has become a significant therapeutic problem. The current research focused on the comparative analysis of the methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA) isolates regarding the demographic features and the mannitol fermentation profiles. Forty eight clinical isolates were examined by conventional microbiological techniques, such as Mannitol Salt Agar (MSA) and biochemical identification. Methicillin resistance was identified by cefoxitin disc diffusion method under the Clinical and Laboratory Standards Institute (CLSI) guidelines. Out of the isolates, 39 (81.25) were MRSA with only 9 (18.75) being MSSA. The results show that most of the patients in the study are dominated by MRSA. Whilst the majority of isolates fermented mannitol, some of the MRSA strains had non-fermenting behavior. Demographic determined that prevalence was higher in the age group (21-40 years old) with minor male preponderation. The research results in a conclusion that though MSA can help in the initial diagnosis of S. aureus, it cannot be depended upon to distinguish MRSA and MSSA. The constant monitoring with the application of standardized antimicrobial susceptibility testing is crucial to the infection control.},
        keywords = {MRSA, MSSA, mannitol fermentation, Mannitol Salt Agar, cefoxitin disc diffusion, Clinical and Laboratory Standards Institute.},
        month = {April},
        }