Cucurbit[6]uril modified platinum electrode for electrochemical detection of Norepinephrine

  • Unique Paper ID: 201861
  • Volume: 12
  • Issue: 12
  • PageNo: 5222-5227
  • Abstract:
  • An electrochemical sensor based on cucurbit [6] uril has been developed for sensitive detection of an important neurotransmitter, norepinephrine (NEP). On a platinum wire electrode, the cucurbit [6] uril solution was drop-casted and is known as a modified electrode. The modified sensor has been characterized by scanning electron microscopy (SEM) to understand the morphological properties of the sensor surface. Electrochemical responses of norepinephrine at a CB [6] modified sensor were investigated by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). CV studies of NEP at the modified electrode were carried out in the potential range of 0 V to 0.8 V in phosphate buffer solution (pH 7.0) and impedance studies at potential 0.4 V in the frequency range of 0.1 Hz to 103 kHz. The modified electrode showed increased current response and decreased charge transfer resistance towards the oxidation of NEP compared to the bare electrode.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{201861,
        author = {Shambhavi and Puja Priyadarshni and Nisha Kumari and Ratnesh Kumar},
        title = {Cucurbit[6]uril modified platinum electrode for electrochemical detection of Norepinephrine},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {12},
        pages = {5222-5227},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=201861},
        abstract = {An electrochemical sensor based on cucurbit [6] uril has been developed for sensitive detection of an important neurotransmitter, norepinephrine (NEP). On a platinum wire electrode, the cucurbit [6] uril solution was drop-casted and is known as a modified electrode. The modified sensor has been characterized by scanning electron microscopy (SEM) to understand the morphological properties of the sensor surface. Electrochemical responses of norepinephrine at a CB [6] modified sensor were investigated by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). CV studies of NEP at the modified electrode were carried out in the potential range of 0 V to 0.8 V in phosphate buffer solution (pH 7.0) and impedance studies at potential 0.4 V in the frequency range of 0.1 Hz to 103 kHz. The modified electrode showed increased current response and decreased charge transfer resistance towards the oxidation of NEP compared to the bare electrode.},
        keywords = {Norepinephrine, Electrode modification, Electrochemical sensor, Electrochemical Techniques, Cyclic Voltammetry, Macrocyclic oligomer.},
        month = {May},
        }

Cite This Article

Shambhavi, , & Priyadarshni, P., & Kumari, N., & Kumar, R. (2026). Cucurbit[6]uril modified platinum electrode for electrochemical detection of Norepinephrine. International Journal of Innovative Research in Technology (IJIRT). https://doi.org/doi.org/10.64643/IJIRTV12I12-201861-459

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