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@article{204564,
        author = {Sushant B. Yedage},
        title = {Analytical Approaches for the Simultaneous Determination of Bronchodilator and Corticosteroid Drugs in Pharmaceutical Formulations A Review},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {1},
        pages = {2541-2545},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=204564},
        abstract = {Respiratory disorders such as asthma and chronic obstructive pulmonary disease (COPD) are commonly treated using combinations of bronchodilator and corticosteroid drugs. Accurate and reliable analytical methods are essential for the quality control, stability assessment, and regulatory compliance of these pharmaceutical formulations. Reverse-phase high-performance liquid chromatography (RP-HPLC) has emerged as one of the most widely used analytical techniques for the simultaneous estimation of respiratory drug combinations due to its high sensitivity, selectivity, precision, and reproducibility. This review summarizes the current approaches employed in RP-HPLC method development and validation for bronchodilator and corticosteroid combinations in bulk drugs and pharmaceutical dosage forms. Key aspects such as chromatographic optimization, mobile phase selection, method validation parameters, and regulatory requirements are discussed. In addition, recent advancements including Quality by Design (QbD), Design of Experiments (DoE), and analytical lifecycle management are highlighted. The review emphasizes the importance of robust analytical methods in ensuring pharmaceutical product quality, safety, and therapeutic efficacy.},
        keywords = {RP-HPLC, Bronchodilator, Corticosteroid, Method Validation, Pharmaceutical Analysis.},
        month = {June},
        }