Ethnopharmacology of Hepatoprotection: A Comprehensive Review of Medicinal Plants with Emphasis on Coptis teeta Wall

  • Unique Paper ID: 171750
  • Volume: 11
  • Issue: 8
  • PageNo: 908-912
  • Abstract:
  • Hepatoprotection, the protection of the liver from damage or disease, remains a critical area of research in pharmacology due to the increasing prevalence of liver-related disorders caused by environmental toxins, infectious agents, and lifestyle factors. Ethnopharmacology, which explores the traditional use of medicinal plants, offers a valuable repository of natural remedies for hepatoprotection. This review aims to comprehensively analyze medicinal plants traditionally used for liver ailments, focusing on their pharmacological mechanisms, bioactive compounds, and clinical relevance. Among these, Coptis teeta Wall, a rare and significant medicinal plant from Eastern Himalayan regions, has drawn attention for its potent hepatoprotective properties. Known for its rich content of alkaloids, especially berberine, Coptis teeta exhibits diverse pharmacological activities, including antioxidant, anti-inflammatory, and anti-apoptotic effects, making it a promising candidate for liver disease management. This paper discusses the traditional uses of Coptis teeta, evaluates its phytochemical composition, and highlights recent advances in understanding its mechanisms of action. Furthermore, it compares the efficacy of Coptis teeta with other ethnomedicinal plants, providing insights into potential therapeutic applications and challenges. This review emphasizes the need for further studies, including preclinical and clinical evaluations, to bridge the gap between traditional knowledge and modern medicine, aiming to develop safe and effective hepatoprotective agents from natural sources.

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