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UV Spectrometric method development and validation of Prazosin HCl in bulk and tablet dosage form

  • Unique Paper ID: 173624
  • Volume: 11
  • Issue: 10
  • PageNo: 935-938
  • Abstract:
  • A simple, precise, accurate and an inexpensive UV spectrophotometric method was developed and validated for Prazosin HCl in active pharmaceutical ingredient and tablet dosage form have been developed and validated as per ICH guidelines. The current study estimated the amount of Prazosin HCl using absorbance values at 246 nm. Detection limit ., quantitation limit [LOQ], linearity, accuracy, and precision have all been statistically validated for the analysis results. A correlation coefficient of 0.9965 indicated that the procedure was linear in the concentration range of 2–10 µg/mL. The validation parameters' results showed that the proposed approach was judged to be appropriate, sensitive, reproducible, accurate, and exact. Therefore, this method proves to be beneficial for regular quality control assessments of Prazosin HCl in both active pharmaceutical ingredients and tablet formulations.
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Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 10
  • PageNo: 935-938

UV Spectrometric method development and validation of Prazosin HCl in bulk and tablet dosage form

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