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@article{184921, author = {Ms. Vaishnavi Madan Chavan and Mr. Kshirsagar N. V.}, title = {FORMULATION AND EVALUATION OF STOMACH SPECIFIC FLOATING IN- SITU GELLING SYSTEM}, journal = {International Journal of Innovative Research in Technology}, year = {2025}, volume = {12}, number = {4}, pages = {3976-3992}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=184921}, abstract = {Aim: - The aim of present study is to Design, Development and Characterization of Stomach Specific Floating In-Situ Gelling System to reduce dose frequency for prolonged period of drug action. Objective: -The objective of research is to Develop and Evaluate In-Situ Floating gelling system to be administered by oral route which upon exposure to Physiologic conditions changes to gel Phase. This novel drug delivery system promotes importantly ease and convenience of administration, deliverance of accurate dose as well as to prolong residence time of drug in contact with mucosa that problems generally encountered in semisolid dosage forms. In situ gel formation occurs due to one or combination of different stimuli like pH change, temperature modulation and solvent exchange. Smart polymeric systems represent promising means of delivering the drugs; these polymers undergo sol-gel transition, once administered.}, keywords = {Floating Drug Delivery System, Gastric retention,}, month = {September}, }
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