Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

@article{185175,
        author = {Dr. Harshad. B and Dr. Ananda Deeban. K. B. S and Dr. Kaarunyan. M},
        title = {Next-Generation Surface Engineering for Optimal Osseointegration: A Synthesis of Emerging Methods and Mechanistic Insights},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {5},
        pages = {203-210},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=185175},
        abstract = {Long-term dental implant stability relies on successful osseointegration, critical for clinical predictability and patient outcomes. Recent advances in surface modification have moved beyond traditional macro- and micro-roughening to nanoscale engineering techniques such as anodization, plasma immersion ion implantation, and laser texturing, which enhance topography, wettability, and protein adsorption at the bone–implant interface. Chemical functionalization with trace element doped hydroxyapatite (e.g., Mg, Si, Sr) improves osteo conductivity and bone bonding, while biologically active coatings deliver osteo inductive growth factors and peptides to promote targeted osteogenesis.
To combat peri-implantitis, antimicrobial strategies using silver nanoparticles, antimicrobial peptides, and multifunctional polymers help prevent microbial colonization, a leading cause of implant failure. Surface chemistry and nano topography also modulate immune responses, particularly macrophage polarization, fostering a regenerative peri-implant environment. Modified surfaces demonstrate superior bone-to-implant contact, biomechanical stability, and faster healing compared to machined implants. However, challenges remain, such as coating durability, immune compatibility, release kinetics, and patient variability, limiting broader clinical use. Future trends focus on integrating nanotechnology, bio functional coatings, and additive manufacturing to create patient-specific, smart implants with enhanced therapeutic precision and durability. This interdisciplinary approach promises more biologically responsive and precise implantology.},
        keywords = {},
        month = {September},
        }