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@article{185368, author = {Kasak Chaudhary and Chhavi Rana and Dr.Lekha Singh and Abhishek kumar and Nikhil Sharma and Vishal Singh and Kuldeep Kumar and Harshita Sharma}, title = {IMPACT OF INTERLEUKIN-6 IN VARIOUS DISEASES CONDITION}, journal = {International Journal of Innovative Research in Technology}, year = {2025}, volume = {12}, number = {5}, pages = {1239-1246}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=185368}, abstract = {Interleukins, a type of signaling protein, aid in cell-to-cell communication within the immune system. Interleukin 6 (IL-6) is a pleiotropic cytokine that has a wide range of functions, including impacts on acute phase reactant pathways, B and T lymphocytes, blood brain barrier permeability, synovial inflammation, hematopoiesis, and embryonic development. This cytokine facilitates the transition between innate and adaptive immune responses by recruiting macrophages and lymphocytes to areas of damage or infection. Diabetes, chronic kidney disease (CKD), and cardiovascular disease (CVD) are three cardiometabolic disorders that continue to be major sources of morbidity and early death. Here, we discuss current knowledge of how anti-inflammatory treatments through suppression of the pro-inflammatory yet pleiotropic cytokine interleukin (IL) 6 may assist patients suffering from these or related disorders or consequences.}, keywords = {Interleukin-6, Diabetes Mellitus, Chronic Kidney Disease, Polycystic Ovary Syndrome, Cardiovascular Disease, Metabolic Syndrome, Subclinical Hypothyroidism.}, month = {October}, }
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