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@article{186534,
        author = {Jitendra Pardesi and Gurunath V. Pandit and Priyanka Jaiswar and Sharada Jadhav},
        title = {Simultaneous Estimation and Quantification of Telmisartan and Cilnidipine Using High Performance Thin Layer Chromatography in Pharmaceutical Dosage},
        journal = {International Journal of Innovative Research in Technology},
        year = {},
        volume = {12},
        number = {no},
        pages = {432-437},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=186534},
        abstract = {This study presents streamlined, highly precise, and efficient HPTLC method for the simultaneous assessment of Telmisartan and Cilnidipine in fixed-dose combination. The chromatographic process utilized aluminium-backed plates coated with silica gel 60 F254 as the stationary phase. A mobile phase consisting of dichloromethane, toluene, and methanol in 7:2:1 (v/v/v) ratio was used. Chromatograms were developed in 10 X 20 cm twin-trough TLC chamber, pre saturated with mobile phase vapor for 20 minutes to ensure optimal separation. Detection was performed at 260 nm, where Distinct and compact spots were observed at Rf values of 0.43 ± 0.05 and 0.55 ± 0.05 for Telmisartan and Cilnidipine respectively, ensuring good resolution. Precision studies were conducted by analyzing the variations in peak responses, expressed as RSD, under both intraday and interday conditions. Accuracy was measured by percentage recovery for Telmisartan and Cilnidipine, and the method was validated according to ICH standards for optimized performance.},
        keywords = {Telmisartan, Cilnidipine, HPTLC, ICH guidelines, Assay.},
        month = {},
        }