Future Prospects and Scientific Foundations of Advanced Sperm Sorting Technologies for Sex Chromosome Selection

  • Unique Paper ID: 188956
  • Volume: 12
  • Issue: 7
  • PageNo: 3947-3950
  • Abstract:
  • The ability to separate X- and Y-chromosome–bearing sperm cells before fertilisation has been a scientific goal for decades. Current technologies, such as flow cytometric sorting, provide moderate accuracy (typically 70–75 percent in practical settings) but are limited by biological constraints, technical noise, and ethical restrictions. This paper examines the underlying biology of sex chromosome differentiation in human sperm, evaluates current sperm-sorting methodologies, and explores future advances in microfluidic engineering, optical discrimination, artificial intelligence enhanced image analysis, and chromosome-specific biochemical tagging. We also discuss legal and ethical issues associated with non-medical sex selection and provide a scientific projection on whether an 80–90 percent reliable sperm sorting system is achievable and socially permissible in the future.

Copyright & License

Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{188956,
        author = {MR. RITAM MONDAL},
        title = {Future Prospects and Scientific Foundations of Advanced Sperm Sorting Technologies for Sex Chromosome Selection},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {7},
        pages = {3947-3950},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=188956},
        abstract = {The ability to separate X- and Y-chromosome–bearing sperm cells before fertilisation has been a scientific goal for decades. Current technologies, such as flow cytometric sorting, provide moderate accuracy (typically 70–75 percent in practical settings) but are limited by biological constraints, technical noise, and ethical restrictions. This paper examines the underlying biology of sex chromosome differentiation in human sperm, evaluates current sperm-sorting methodologies, and explores future advances in microfluidic engineering, optical discrimination, artificial intelligence enhanced image analysis, and chromosome-specific biochemical tagging. We also discuss legal and ethical issues associated with non-medical sex selection and provide a scientific projection on whether an 80–90 percent reliable sperm sorting system is achievable and socially permissible in the future.},
        keywords = {},
        month = {December},
        }

Cite This Article

  • ISSN: 2349-6002
  • Volume: 12
  • Issue: 7
  • PageNo: 3947-3950

Future Prospects and Scientific Foundations of Advanced Sperm Sorting Technologies for Sex Chromosome Selection

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