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@article{191170,
        author = {Roshani satish darekar and Dr. mangal.s.gaikwad and Neha pradip masalkar},
        title = {lutein - a comprehensive review of its pharmacological and therapeutic potential},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {5869-5880},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=191170},
        abstract = {Lutein is a naturally occurring xanthophyll carotenoid widely present in green leafy vegetables, fruits, and egg yolk. It is a lipid-soluble bioactive compound recognized for its significant pharmaceutical and nutraceutical importance, particularly in the prevention and management of ocular disorders. Lutein selectively accumulates in the macula and lens of the human eye, where it acts as a natural antioxidant and blue-light filter, thereby protecting retinal tissues from oxidative stress and photochemical damage. Numerous clinical and epidemiological studies have demonstrated its beneficial role in reducing the risk of age-related macular degeneration, cataracts, and other vision-related disorders. In addition to ocular health, lutein exhibits anti-inflammatory, neuroprotective, and cardioprotective properties, highlighting its broader therapeutic potential. Since lutein cannot be synthesized by the human body, adequate dietary intake and supplementation are essential. However, its poor water solubility and low bioavailability present formulation challenges, leading to the development of advanced pharmaceutical and nutraceutical delivery systems. This review focuses on the chemical nature, sources, pharmacological activities, therapeutic applications, and formulation strategies of lutein, emphasizing its growing role as a functional nutraceutical and preventive therapeutic agent.},
        keywords = {Lutein; Xanthophyll carotenoid; Antioxidant activity; Ocular health; Age-related macular degeneration; Nutraceuticals; Pharmaceutical applications; Bioavailability},
        month = {January},
        }