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@article{195684,
        author = {Jaydeep V. Rathod and Khushbu S. Jaiswal and M. M. Kodape and N. D. Gawhale},
        title = {Development of Substituted Diazoles with Potential Pharmacological Activities},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {no},
        pages = {92-95},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=195684},
        abstract = {Diazole derivatives are an important class of heterocyclic compounds known for their wide-ranging pharmacological properties, including antimicrobial, anticancer, anti-inflammatory, and enzyme inhibitory activities. In this study, a series of substituted diazoles were designed and synthesized using efficient synthetic methodologies to introduce structural diversity. The structures of the synthesized compounds were confirmed through spectroscopic techniques such as NMR, IR, and mass spectrometry. Preliminary biological evaluations were performed to assess their pharmacological potential, including antimicrobial screening and cytotoxicity assays. Several derivatives demonstrated significant biological activity, and structure–activity relationship (SAR) analysis suggested that the type and position of substituents critically influenced bioactivity. These findings highlight substituted diazoles as promising scaffolds for further drug development and provide valuable insights into the relationship between molecular structure and pharmacological efficacy.},
        keywords = {Substituted Diazoles, Heterocyclic Compounds, Chemical Synthesis, Biological Evaluation, Pharmacological Activity},
        month = {March},
        }