Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

@article{195751,
        author = {Saleha Anjum Mohd. Shakeel and Khushbu S. Jaiswal and M.M. Kodape and N.D. Gawhale},
        title = {Synthesis And Biological Evaluation of Substituted Hydroxyl Dihydroisoxazole Derivatives},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {no},
        pages = {211-215},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=195751},
        abstract = {Dihydroisoxazoles are an important class of heterocyclic compounds that have attracted considerable attention due to their diverse biological and pharmacological properties. In the present study, a series of substituted hydroxyl dihydroisoxazole derivatives were synthesized using an efficient and straightforward synthetic methodology. The reactions were performed under optimized conditions, affording the target compounds in good to excellent yields. The structures of the synthesized derivatives were confirmed by spectroscopic techniques, including 1H NMR GC-MS. The synthesized compounds were evaluated for their biological activities using standard in vitro assays. Several derivatives exhibited promising biological activity, indicating that the presence and position of hydroxyl substituents play a crucial role in influencing biological performance. The results of this study suggest that substituted hydroxyl dihydroisoxazole derivatives may serve as potential lead compounds for further pharmacological development.},
        keywords = {Dihydroisoxazole derivatives, Hydroxyl-substituted heterocycles, Heterocyclic synthesis, biological evaluation, Structure activity relationship},
        month = {March},
        }