Nanoparticles for Cancer Therapy: A Revolution in Precision Oncology

Shivam Kumar; Alok Kumar Jha; Pallavi Chand; Vikash Jhakhmola

Nanoparticles for Cancer Therapy: A Revolution in Precision Oncology

Authors: Shivam Kumar, Alok Kumar Jha, Pallavi Chand, Vikash Jhakhmola

Unique Paper ID: 179149
Volume: 11
Issue: 12
PageNo: 5765-5778

Keywords: Cancer Chemotherapy Nanoparticles Cellular Targeting Multidrug Resistance Drug Delivery.

Abstract:
Cancer continues to be one of the leading causes of morbidity and mortality worldwide, owing to its complicated pathophysiology and limits in standard therapies such as chemotherapy, radiation, and immunotherapy. These old techniques frequently have limitations, including as cytotoxicity, lack of selectivity, and the formation of multidrug resistance. The development of nanotechnology has resulted in a paradigm change in cancer diagnosis and therapy. Nanoparticles (1-100 nm) have improved permeability and retention, lower toxicity, higher stability, biocompatibility, and precision targeting, making them a suitable vehicle for drug delivery and imaging applications. They address traditional treatment difficulties by increasing drug solubility, enabling tailored therapy, and boosting immune response modulation. This review investigates the role of several nanoparticles liposomes, polymeric nanoparticles, dendrimers, quantum dots, and silica nanoparticles in cancer therapy. In addition, it discusses their mechanics, therapeutic applications, and ongoing advances in nanoparticle-based therapy. While nanoparticles have enormous potential for personalized medicine and better therapeutic outcomes, their environmental and societal effects must be carefully evaluated as these technologies get closer to clinical implementation.

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Cite This Article

ISSN: 2349-6002
Volume: 11
Issue: 12
PageNo: 5765-5778

Nanoparticles for Cancer Therapy: A Revolution in Precision Oncology

Available:https://ijirt.org/Article?manuscript=179149

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