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@article{186693,
        author = {Syeda Suwaiba Fathima and Dr Prashanthi P and Dr. Sathish Rajendran and Dr. Lakshmi Priya and Dr. Annie Arockia Mary and Dr. Jaideep Mahendra},
        title = {Current Advances and Emerging Frontiers in Periodontal Regeneration: From Biology to Biomaterials},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {6},
        pages = {1774-1782},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=186693},
        abstract = {To restore the structural and functional integrity of the tooth-supporting tissues—such as the gingiva, periodontal ligament, cementum, and alveolar bone—that are weakened by periodontitis, periodontal regeneration is a crucial component of contemporary periodontics. With a focus on the functions of stem cell-based therapy, growth factor-mediated signaling, bioactive scaffolds, nanostructured biomaterials, and new gene and cell-free techniques, this study offers a thorough summary of current developments in periodontal regenerative techniques. While nanotechnology has improved the targeted delivery and regulated release of bioactive chemicals, the development of novel biomaterials and three-dimensional (3D) printed scaffolds has improved the capacity to reproduce the intricate architecture of the periodontium. Furthermore, potential cell-free substitutes that encourage tissue regeneration and control the host inflammatory response are exosome-based and bio-engineered constructions. Despite these significant advancements, there are still issues with cost, scalability, immunological compatibility, and the clinical application of lab results. In order to develop individualized and clinically dependable regenerative therapies that can produce predictable, functional periodontal restoration, future research should concentrate on combining molecular biology, materials science, and tissue engineering.},
        keywords = {Periodontal regeneration, Stem cell therapy, Nanotechnology, Scaffolds, Growth factors, Exosomes},
        month = {November},
        }