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@article{202899,
        author = {Aishwarya Bhaskar Kamble and Deepak Dnyaneshwar Ghotale},
        title = {Formulation and Optimization of Fast Dissolving Tablets of Etoricoxib Using Solid Dispersion Technique},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {12},
        pages = {8255-8259},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=202899},
        abstract = {Fast Dissolving Tablets (FDTs) of Etoricoxib were formulated and optimized using solid dispersion technique with superdisintegrants Crospovidone and Croscarmellose Sodium. Etoricoxib, a selective COX-2 inhibitor (BCS Class II drug), suffers from poor aqueous solubility leading to delayed onset of action. Five formulations (F1–F5) were prepared by solid dispersion method with varying concentrations of superdisintegrants. All formulations were evaluated for precompression and postcompression parameters. Formulation F3 containing 9 mg Crospovidone demonstrated superior performance with disintegration time of 21 seconds and drug release of 99.9% within 30 minutes. Accelerated stability studies at 40°C ± 2°C / 75% ± 5% RH for 3 months confirmed stability of the optimized formulation. The results indicate that fast dissolving tablets of Etoricoxib can be successfully developed using solid dispersion technique, offering rapid onset of analgesic action and improved patient compliance.},
        keywords = {Etoricoxib, Fast Dissolving Tablets, Crospovidone, Croscarmellose Sodium, Solid Dispersion, Superdisintegrants, BCS Class II.},
        month = {May},
        }