Eczema: A Comprehensive view on Treatment Modalities
Author(s):
chetana shelote, Charvi Kubde, Dr. Nishant Awandekar, Dr. Milind Umekar
Keywords:
Atopic Dermatitis, Glucocorticoids, Tacrolimus, Pimecrolimus.
Abstract
Eczema is a chronic inflammatory skin condition that has become almost epidemic among children. The therapeutic approach for Atopic Dermatitis (AD) demands for a protracted course of therapy. By introducing the first biologic medication, treatment options for AD recently underwent a radical transformation. Basic, Topical and systemic therapy for AD patients, including children and adults, are the main topics of the modified guidelines that are described here. If conservative measures are unsuccessful in providing enough symptom relief, standard medical care including a pharmaceutical strategy may be required. Recently, proactive treatment methods that include intermittent, daily applications of topical calcineurin inhibitors or low-potency steroids to avoid future flares have received increased attention. Basic therapy concentrates on moisturising topical treatment and avoiding both particular and general provocation factors. Topical glucocorticoids and topical calcineurin inhibitors (TCI)-based anti-inflammatory therapy is utilised for exacerbation management and, more recently, for proactive therapy in some situations. Although tacrolimus and pimecrolimus from the TCI are favoured in some areas, topical corticosteroids remain the cornerstone of therapy. For extreme refractory instances, systemic immune-suppressive therapy is an option. Superinfection and microbial colonisation may exacerbate disease and warrant further antimicrobial therapy. Adjuvant therapy includes exposure to UV light, preferably at UVA1 or UVB 311 nm. Various targeted biologics are also being introduced for AE management and are being touted as effective treatments. This article offers a treatment recommendation and a description of recent research on the management of AD.
Article Details
Unique Paper ID: 161480

Publication Volume & Issue: Volume 10, Issue 4

Page(s): 155 - 165
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