Blockchain technology is uprising and gaining traction in this world of technology and is now used to solve a wide range of tasks. Blockchain technology is present in financial sector, IOT networks, crypto currency and in many other fields. If we see the security measures, blockchain itself vulnerable to lots of risk. As Blockchain contain confidential information about infrastructure and assets of specific user and business, providing extensive protection is important. Blockchain is already a secure mechanism but due to fast advancement in technology it must be updated with latest threats. However, this paper is going to show the role of blockchain technology to strengthen the various domain such as networking, Internet of Things, cyber security, financial and medical sector and also in other domains.