Synthesis, characterization and antimicrobial studies of 3-methoxy-4-hydroxy benzaldehyde & o-phenylene diamine Schiff base ligand and its mixed ligand metal complex synthesized by microwave assisted method
Sridevi S P, Dr. Girija C R, Dr Satish C D, Prashantha Karunakar
Benzimidazole, Schiff base mixed ligand, 3-methoxy-4-hydroxy benzaldehyde, o-phenylene diamine, acetylacetonate (acac), antibacterial, antifungal and Gentamycin and Nystatin.
Benzimidazole Schiff base ligand of 3-methoxy-4-hydroxy benzaldehyde and o-phenylene diamine, acts as anti-bacterial and anti-fungal agent. Recent studies reveal their ability to exhibit anti-proliferative, anticancer, antioxidant properties in drug chemistry. In this work, 4-[1-(4-Hydroxy-3-methoxybenzyl)-2,3-dihydro-1H-benzimidazol-2-yl]-2-methoxyphenol ligand and the chelating mixed acac complex of 4-[1-(4-Hydroxy-3-methoxybenzyl)-2,3-dihydro-1H-benzimidazol-2-yl]-2-methoxyphenol were prepared by microwave assisted, are reported. All the isolated Schiff base ligand and mixed acac metal complex were characterized by using IR, 1H NMR, UV-VIS and TGA/DTA analysis. The biological activities of all the isolated ligands and their corresponding mixed acac metal complexes have been used to screening against the microorganisms both gram positive and gram negative and the results were compared with standard.
Article Details
Unique Paper ID: 150997

Publication Volume & Issue: Volume 7, Issue 11

Page(s): 347 - 354
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