Synthesis Thermal Analysis of Bio active Glass In Vitro characterization

Synthesis Thermal Analysis of Bio active Glass In Vitro characterization
Author(s):
Shaik Pharuk, Dr.P.Vijay Kumar
Keywords:
SBF, Bioactivity, Bioactive glasses, Apatite, Vitro, Implantation
Abstract
In this study, the synthesis of P2O5-CaCO3-Na2CO3-K2CO3-SrO bioactive glass was performed by the conventional glass manufacturing method. The bio glass material was produced by sintering at 900oC. The obtained material was evaluated by Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscope (SEM) and Differential Thermal Analysis (DTA). The biocompatibility evaluation of the formed glass was assessed through in vitro cell culture experiments and immersion studies in simulated body fluid (SBF) for different time intervals while monitoring the pH changes and the concentrations in the SBF medium. The SEM, FTIR and DTA studies were conducted after soaking of the material in SBF. At first, an amorphous calcium phosphate was formed; after 18 days this surface consisted of deposited crystalline apatite. The present investigation also revealed that the bio glass system has the ability to support the growth of human bone cells. Bioactive materials can help bone reparation and regeneration by offering support to bone growth. Finally, this material proved to be non-toxic and compatible.
Article Details
Unique Paper ID: 143902 Publication Volume & Issue: Volume 3, Issue 3 Page(s): 153 - 159
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