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@article{150441,
        author = {Nagma Begum and Dr.M.Vijaya Bhargavi and Dr.M.Sumakanth},
        title = {RESEARCH ARTICLE ON SYNTHESIS, CHARACTERIZATION, MOLECULAR DOCKING AND BIOLOGICAL EVALUATION OF 6-METHOXY-BENZOTHIAZOL-2-YL-AMIDE DERIVATIVES},
        journal = {International Journal of Innovative Research in Technology},
        year = {},
        volume = {7},
        number = {6},
        pages = {111-122},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=150441},
        abstract = {Benzothiazole is a privileged fused heterocyclic moiety, has attracted synthetic and medicinal chemists for good reasons. It is a valuable scaffold that possesses diverse biological activities, such as antimicrobial, antitubercular, antitumor, antimalarial, anticonvulsant, anthelmintic, analgesic and anti-inflammatory activity and other miscellaneous activities which makes benzothiazole an interesting molecule for the researchers to work on. Six derivatives of 6-methoxy-benzothiazol-2-yl-amide derivatives were subjected to in silico docking studies with the help of N-Myristoyltransferase (PDB ID:1ZAP). 2-amino-6-methoxy benzothiazole reacted with acid chlorides, to obtain a final product 6-methoxy-benzothiazol-2-yl-amide derivatives. The newly synthesized derivatives are characterized by using IR, 1H NMR and Mass spectral data. From the docking results the compounds showed moderate to good activity which was comparable to that of the standard Fluconazole drug.},
        keywords = {Benzothiazoles, 2-amino-6-methoxy benzothiazole, Fluconazole and N-Myristoyltransferase},
        month = {},
        }