ORAL MUCOADHESIVE DRUG DELIVERY SYSTEMS: A REVIEW
Author(s):
Dr Satpute K.L, Jadhav Madhav, Panchal Ashitosh
Keywords:
Mucoadhesion, Bioadhesion, Oral mucosa, Mucin, Mucus, Hydrogels.
Abstract
This article focuses on defining the principles of bioadhesive delivery systems based on hydrogels to biological surfaces that are covered by mucus. An overview of the last decade’s discoveries on mucoadhesion and applications of mucoadhesive hydrogels as drug carriers is given. Techniques that are frequently used to study the adhesion forces and physicochemical interactions between hydrogel, mucus, and the underlying mucosa are reviewed. Mucoadhesion can be defined as a state in which two components, of which one is of biological origin are held together for extended periods of time by the help of interfacial forces mucoadhesion is the attachement of the drug along with a suitable carrier to the mucous membrane. Mucoadhesion is a complex phenomenon which involves wetting, adsorption and interpenetration of polymer chains. Thereafter, several researchers have focused on the investigations of the interfacial phenomena of mucoadhesion with the mucus. The polymers used for formulation of mucoadhesive drug delivery systems are poly acrylic acid derivatives, chitosan and newer second generation polymers. Mucoadhesive drug delivery systems with its various advantages have a lot of potential in formulating dosage forms for various chronic diseases.
Article Details
Unique Paper ID: 150453

Publication Volume & Issue: Volume 7, Issue 6

Page(s): 123 - 135
Article Preview & Download


Share This Article

Conference Alert

NCSST-2021

AICTE Sponsored National Conference on Smart Systems and Technologies

Last Date: 25th November 2021

SWEC- Management

LATEST INNOVATION’S AND FUTURE TRENDS IN MANAGEMENT

Last Date: 7th November 2021

Go To Issue



Call For Paper

Volume 9 Issue 10

Last Date for paper submitting for March Issue is 25 March 2023

About Us

IJIRT.org enables door in research by providing high quality research articles in open access market.

Send us any query related to your research on editor@ijirt.org

Social Media

Google Verified Reviews

Contact Details

Telephone:6351679790
Email: editor@ijirt.org
Website: ijirt.org

Policies