Phytochemical investigation and evaluation of Anti-inflammatory activity of Camellia sinensis (Green Tea) leaves in Experimental Animals
Author(s):
Nagma Khan, Dr. Hemant Swami, Pooja Gourav, Monesh Kushwah, Pooja Raj
Keywords:
Camellia sinensis; anti-inflammatory; Arachidonic acid; Standardization
Abstract
Present work to evaluate anti-inflammatory activity of Camellia sinensis (Green Tea). Pharmacological studies were carried out with methanol-water (1:1) extract of green tea (Camellia sinensis) leaves extract. Leaves extract was found to possess anti-inflammatory, analgesic and antipyretic activities at 1/10th of its LD50 dose of 40 mg/kg i.p. Phytochemical parameter also perform like extractive value, ash value, loss on drying etc. to check the standardization of plant extract. It was found that leaves extract inhibited the arachidonic acid-induced paw edema in rats which indicated that leaves extract produced the anti-inflammatory activity by inhibiting both the cyclooxygenase and lypooxygenase pathways of arachidonic acid metabolism. Leaves extract enhanced peritoneal cell count and the number of macrophages in normal mice. It is possible that the saponins present in leaves extract may be responsible for these activities of Green tea leaves extract.
Article Details
Unique Paper ID: 151936

Publication Volume & Issue: Volume 8, Issue 2

Page(s): 156 - 161
Article Preview & Download


Share This Article

Conference Alert

NCSST-2021

AICTE Sponsored National Conference on Smart Systems and Technologies

Last Date: 25th November 2021

SWEC- Management

LATEST INNOVATION’S AND FUTURE TRENDS IN MANAGEMENT

Last Date: 7th November 2021

Go To Issue



Call For Paper

Volume 9 Issue 10

Last Date for paper submitting for March Issue is 25 March 2023

About Us

IJIRT.org enables door in research by providing high quality research articles in open access market.

Send us any query related to your research on editor@ijirt.org

Social Media

Google Verified Reviews

Contact Details

Telephone:6351679790
Email: editor@ijirt.org
Website: ijirt.org

Policies