Development of colon drug delivery system for the treatment of inflammatory bowel disease
Author(s):
Akhilkumar G Sonkamble, Qureshi S.N, Nandkishor B Bawage, Dr. Shaymlila B Bawage
Keywords:
Inflammatory bowel disease, colon drug delivery systems, OROS-CT, pH-dependent carriers, CODESTM , novel colon approaches
Abstract
Inflammatory bowel disease (IBD) is one of the most common chronic diseases that affect the entire gastrointestinal tract (GIT) especially the colon. Its symptoms extend from mild diarrhea, abdominal pain, and bloody diarrhea to severe conditions which affect the quality of life. Many treatments have been developed to treat and cure IBD and to improve patient’s quality of life. The big challenge faces the newly developed treatments is the site of action as the colon presents at the distal end of the GIT and have a complex biological environment. Many technologies have been investigated to target the colon, load higher amounts of active ingredients, and decrease unwanted side effects resulted from upper GIT absorption. This review briefly discusses the IBD, treatment lines, physiological considerations, and all methods of colon targeting technologies starting from the traditional methods which based on pH, time, and microbial content of the colon. Also, we discussed in detail all new techniques based on Micro and Nanotechnology which improve the effectiveness of used therapeutics.
Article Details
Unique Paper ID: 152257

Publication Volume & Issue: Volume 8, Issue 2

Page(s): 860 - 870
Article Preview & Download


Share This Article

Conference Alert

NCSST-2023

AICTE Sponsored National Conference on Smart Systems and Technologies

Last Date: 25th November 2023

SWEC- Management

LATEST INNOVATION’S AND FUTURE TRENDS IN MANAGEMENT

Last Date: 7th November 2023

Go To Issue



Call For Paper

Volume 10 Issue 1

Last Date for paper submitting for March Issue is 25 June 2023

About Us

IJIRT.org enables door in research by providing high quality research articles in open access market.

Send us any query related to your research on editor@ijirt.org

Social Media

Google Verified Reviews