Ufasomes: A Potential Vesicular Drug Delivery System
Author(s):
D T Krishna Sinjitha, Dr. K. V. Ratnamala
Keywords:
Liposomes, niosomes, transferosomes, ufasomes
Abstract
Many Novel Vesicular Delivery systems have been discovered to administer drugs for controlled and targeted delivery. These vesicular systems include liposomes, niosomes, transferosomes, ethosomes, ufasomes, etc. Ufasomes are unsaturated fatty acid vesicles. They are suspensions of fatty acid and their ionized species( soap) which are arranged as closed lipid bilayers that are restricted to narrow pH range from 7 to 9. They are obtained from unsaturated fatty acids such as oleic acid, arachidonic acid, linoleic acid etc. The fatty acid molecules in the ufasomes are arranged in such a manner that the hydrocarbon tails is faced inwards while the carboxyl groups are in contact with aqueous media. The study focuses on the advantages and disadvantages, method of preparation and characterization of ufasomes.
Article Details
Unique Paper ID: 152655
Publication Volume & Issue: Volume 8, Issue 3
Page(s): 1100 - 1105
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