An Overview on Nanoparticle-Enabled Wound Dressing Patch
Author(s):
Nisha Thakre
Keywords:
Nanoparticles, TDDS, Microneedles, Transdermal patches, Wound healing patch.
Abstract
The word "nanoscale" refers to particle sizes ranging from 1 to 100 nanometers; however nanoparticles in the range of 50 to 500 nanometers are suitable for medication delivery depending on the route of administration. The way a medication is administered can have a big impact on its effectiveness. When topical, regional, or systemic effects are required, the skin has long been a popular route for drug administration. Because of electrostatic interactions, nanoparticles have a strong affinity for biological membranes. Some studies have discovered that surface charge has an impact on membrane permeability, for example, the polymer charge density of dendrimers has been found to have a substantial impact on membrane permeability. Nanoparticles (NPs), which have the potential to improve medication penetration over the skin, have been used in recent developments in TDDS. NPs can also offer controlled release, administer both hydrophilic and hydrophobic medicines, and decrease adverse effects, and they are non-invasive when employed in a TDDS manner. Skin patches with microneedles are another emerging technique for TDDS. New studies have focused on incorporating two TDDS techniques to overcome the limitations of traditional drug delivery systems. Loaded nanoparticles are used to create the structures, which may also be used to make patches and wound healing materials. The goal of this review paper is to show how such patches and wound dressings may be processed in new ways.
Article Details
Unique Paper ID: 152709

Publication Volume & Issue: Volume 8, Issue 4

Page(s): 121 - 130
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