AQUASOMES: A Nano-Particulate Carrier System

AQUASOMES: A Nano-Particulate Carrier System
Author(s):
Syeda Ruhina Anjum, Dr K.V. Ratnamaala
Keywords:
Aquasomes, van der waals forces, insulin, serratiopeptidase.
Abstract
Aquasomes are nanoparticulate carrier system that ranges from 60-300 nanometre in size, but instead of being simple nanoparticles theses are three layered self-assembled structures, comprised of a solid phase nanocrystalline core coated with oligomeric film to which bio chemically active molecules are absorbed with or without modification .The solid core provides the structural ability , while the carbohydrate coating plays important role act as natural stabilizer protects against dehydration and stabilizes the biochemically active molecule.Aquasomes possess large size and active surface and hence can be efficiently loaded with substantial amounts of agents through ionic, non-covalent bonds, van der waals forces and entropic forces. As solid particles dispersed in aqueous environment exhibit physical properties of colloids. Poorly water soluble drugs, insulin,hemoglobin, serratiopeptidase can be delivered.
Article Details
Unique Paper ID: 152805 Publication Volume & Issue: Volume 8, Issue 4 Page(s): 532 - 535
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