Nanocrystals In Drug Delivery- A Review
Author(s):
Kalyani A. Ghadge, Ashwini A Pawar, Rupali B. Kewat, Aijaz A.Sheikh, Ravindra H. Kale, Kaiash R. Biyani
Keywords:
Nanocrystal, Drug delivery, Bioavailability, polymeric nanocrystals, techniques.
Abstract
Nanocrystals are the aggregates anywhere from a few hundred to tens of thousands of atoms that combine into a crystalline form of matter known as a “ Cluster “ .They are used as a physical approach to alter and improve the pharmacokinetic and pharmacodynamic properties of various types of drug molecules. They have been used in vivo to protect the drug entity in the systemic circulation. The method of preparations of nanocrystal is down, top down and bottom up, spray drying and so new techniques. There are several important advantages of nanocrystal formulation such as, enhanced oral bioavailability, improved dose proportionality, reduced food effects, suitability for administration by all routes and possibility of sterile filtration due to decreased particle size range. Selection depends upon the sites and to deliver the drug at a controlled sustained rate to the site of action. Here we review various aspects of nanocrystals in drug delivery and their pharmaceutical applications in drug delivery.
Article Details
Unique Paper ID: 153911

Publication Volume & Issue: Volume 8, Issue 9

Page(s): 462 - 469
Article Preview & Download


Share This Article

Conference Alert

NCSST-2021

AICTE Sponsored National Conference on Smart Systems and Technologies

Last Date: 25th November 2021

SWEC- Management

LATEST INNOVATION’S AND FUTURE TRENDS IN MANAGEMENT

Last Date: 7th November 2021

Go To Issue



Call For Paper

Volume 8 Issue 4

Last Date 25 September 2021

About Us

IJIRT.org enables door in research by providing high quality research articles in open access market.

Send us any query related to your research on editor@ijirt.org

Social Media

Google Verified Reviews

Contact Details

Telephone:6351679790
Email: editor@ijirt.org
Website: ijirt.org

Policies