Review on the Synthesis and characterization of N-5{Acridin-9yl)-2-chloro phenyl}alkyl]aryl amides/imides possessing  Antimicrobial activity

RENU SINGH

Review on the Synthesis and characterization of N-5{Acridin-9yl)-2-chloro phenyl}alkyl]aryl amides/imides possessing Antimicrobial activity

Authors: RENU SINGH

Unique Paper ID: 154330
Volume: 8
Issue: 10
PageNo: 551-555

Keywords: Acridine derivatives Animal charcoal diphenyl derivatives.

Abstract:
An equivalent mixture of Diphenylamine and 4-chloro benzoic acid was heated in the presence of anhydrous ZnCl2 in ethanol. After few hours crude was extracted with benzene, then boiled with charcoal, filtered to get 9-(4-chlorophenyl)-acridine crystal (I). A finally powdered mixture of (I) and an appropriate amido/ imido alkylol (II) was dissolved in concentrated sulphuric acid which furnished N-[5-acridin-9-yl)-2-chlorophenyl}alkyl]-aryl amides/imides(III). Compound (III) were screened for their antimalarial activity involving the standardized method as recommended by National Committee on Clinical Laboratory Standards (NCCLS).

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ISSN: 2349-6002
Volume: 8
Issue: 10
PageNo: 551-555

Review on the Synthesis and characterization of N-5{Acridin-9yl)-2-chloro phenyl}alkyl]aryl amides/imides possessing Antimicrobial activity

Available:https://ijirt.org/Article?manuscript=154330

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8.01 (Year 2024)

UGC Approved
Journal no 47859

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