A REVIEW ARTICLE ON PULMONARY DRUG DELIVERY SYSTEM
Author(s):
ABDUL MANNAN, ZEBA MOHIUDDIN, SHAIK AMEER AHMED, MIRZA WAJAHAT BAIG, FIRDOUS FATIMA
Keywords:
pulmonary drug delivery, nasal drug delivery, targeted drug delivery, delivery devices, formulation approaches, strategies.
Abstract
In present study authors review all aspects of pulmonary drug delivery system; including need of drug delivery, different approaches for drug delivery and recent advancement in pulmonary drug delivery system. Apart from various formulations, different delivery devices such as metered dose inhalers (MDI), dry powder inhalers (DPI), nebulizers, aerosolizers, etc. have also improved drug targeting efficacy and reduced dose size in a more efficient manner. Many drug delivery devices for nasal application of liquid, semisolid and solid formulation are investigated to deliver the drugs to the treat most crisis CNS diseases (i.e., Parkinson’s disease, Alzheimer’s disease) because it requires rapid and/or specific targeting of drugs to the brain. This review contains mainly the tabulated description of different categories of drugs and devices recently available in the market which makes it easily accessible for the researchers. It can be concluded from whole study that different pulmonary delivery system possesses certain specificity for dosage formulations and serves as an important tool to deliver drugs to the target site.This review sets out to discuss some factors affecting nasal absorption, bioavailability barriers, strategies to improve nasal absorption, new developments in nasal dosage form design and applications of nasal drug delivery system.
Article Details
Unique Paper ID: 155172

Publication Volume & Issue: Volume 9, Issue 1

Page(s): 50 - 59
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