Author Login IJIRT Partner Network (IPN) Login

ANALYTICAL METHOD DVELOPMENT AND VALIDATION OF EFONIDIPINE HYDROCHLORIDE ETHANOLATE IN BULK AND DOSAGE FORM BY UV-VISIBLE SPECTROPHTOMETRY

  • Unique Paper ID: 155400
  • Volume: 9
  • Issue: 1
  • PageNo: 838-843
  • Abstract:
  • A simple, precise, accurate, economical and reliable UV Spectrophotometric method has been developed for the estimation of Efonidipine in tablet dosage form. The drug shows maximum absorption at 253 nm in methanol and obeys Beer’s law in the concentration range of 10-30 μg /mL with good correlation coefficient (R2=0.997). The results of analysis were validated by recovery studies. The recovery was found to be 96-99 %. Limit of detection (LOD) and limit of quantification (LOQ) were found to be 2.82 μg/ml and 8.57μg/ml respectively. The relative standard deviation was found to be < 2.0 % in all cases. The Proposed Spectrophotometric method was validated as per the ICH Q2 (R1) guidelines. The proposed method can be used for the reliable quantification of Efonidipine in bulk form and routine analysis of pharmaceutical formulations.
Download article email to a friend

Cite This Article

  • ISSN: 2349-6002
  • Volume: 9
  • Issue: 1
  • PageNo: 838-843

ANALYTICAL METHOD DVELOPMENT AND VALIDATION OF EFONIDIPINE HYDROCHLORIDE ETHANOLATE IN BULK AND DOSAGE FORM BY UV-VISIBLE SPECTROPHTOMETRY

Related Articles

Impact Factor
8.01 (Year 2024)
UGC Approved
Journal no 47859

Join Our IPN

IJIRT Partner Network

Submit your research paper and those of your network (friends, colleagues, or peers) through your IPN account, and receive 800 INR for each paper that gets published.

Join Now

Latest Publication

Archive

View More

Recent Conferences

NCSEM 2024

National Conference on Sustainable Engineering and Management - 2024 Last Date: 15th March 2024

Submit inquiry