Author Login IJIRT Partner Network (IPN) Login

Neurofibromatosis type-1: A Narrative Review on Epidemiology, Clinical Manifestations and Management

  • Unique Paper ID: 157908
  • Volume: 9
  • Issue: 8
  • PageNo: 242-245
  • Abstract:
  • One in 2,500 persons worldwide have neurofibromatosis type 1 (NF1), a prevalent neurogenetic condition. There is a 50% chance of passing it on to their offspring because it is an autosomal dominant disorder. Café-au-lait macules, neurofibromas or plexiform neurofibroma, skinfold freckling, an optic pathway tumour, two or more iris hamartomas, a distinctive bone lesion, or a first-degree relative with NF1 are required for the diagnosis of NF1. Café-au-lait spots, freckled skin folds, generalised hyperpigmentation, blue-red and pseudoatrophic macules, plexiform neurofibroma, juvenile xanthogranuloma, glomus tumour, melanoma, nevus anemicus, and pruritus are examples of cutaneous manifestations of NF1. Learning difficulties and attention deficit hyperactivity disorder (ADHD) are among the NF1 non-cutaneous manifestations, as are orthopaedic, neurologic/psychiatric, ophthalmologic, and other conditions. Treatment options for NF1 include genetic counselling, referrals to other experts, and therapies like speech, occupational, or physical therapy. To create new treatments for NF1, ongoing research is being done.
Download article email to a friend

Cite This Article

  • ISSN: 2349-6002
  • Volume: 9
  • Issue: 8
  • PageNo: 242-245

Neurofibromatosis type-1: A Narrative Review on Epidemiology, Clinical Manifestations and Management

Related Articles

11 Nov, 2022

A Survey on Depression in Students of Pharmacy

Read More
Impact Factor
8.01 (Year 2024)
UGC Approved
Journal no 47859

Join Our IPN

IJIRT Partner Network

Submit your research paper and those of your network (friends, colleagues, or peers) through your IPN account, and receive 800 INR for each paper that gets published.

Join Now

Latest Publication

Archive

View More

Recent Conferences

NCSEM 2024

National Conference on Sustainable Engineering and Management - 2024 Last Date: 15th March 2024

Submit inquiry