Author Login IJIRT Partner Network (IPN) Login

FORMULATION AND IN VITRO EVALUATION OF SUSTAINED RELEASE TABLETS OF VENLAFAXINE HCl

  • Unique Paper ID: 158123
  • Volume: 9
  • Issue: 8
  • PageNo: 742-746
  • Abstract:
  • The sustained release tablets of venlafaxine HCl were prepared by direct compression method using release retarding ability of different grades of HPMC polymers (E4M, E15LV & E50LV) and eudrgit L 100 to extend the release of drug over 24hrs period and thereby improve its bioavailability. The developed tablets were evaluated for pre-compression and post-compression parameters. The results of all formulations were found within the pharmacopeial limits. The optimized formulation (F7) with HPMC E50LV showed the maximum percentage of drug release for 24 hrs was 99.76%. The results indicated that at higher viscosity grades of polymer concentrations drug release was retarded greatly were observed. The drug release was showed by higuchi model followed by zero order release.
Download article email to a friend

Cite This Article

  • ISSN: 2349-6002
  • Volume: 9
  • Issue: 8
  • PageNo: 742-746

FORMULATION AND IN VITRO EVALUATION OF SUSTAINED RELEASE TABLETS OF VENLAFAXINE HCl

Related Articles

03 Oct, 2024

Phytochemical Investigation, Antioxidant and Antimicrobial Activities of Terminalia Bellerica Fruit Extract

Read More
09 Apr, 2024

Formulation development, in vitro and in vivo studies of eprosartan mesylate loaded solid lipid nanoparticles for improved bioavailability

Read More
02 Apr, 2023

ANTIUROLITHIATIC ACTIVITY OF ETHANOLIC EXTRACT OF CUCUMIS SATIVUS FRUIT IN WISTAR RATS

Read More
01 Apr, 2023

DEVELOPMENT AND CHARACTERIZATION OF QUINAPRIL CO-CRYSTALS USING NEUTRACEUTICALS AS CO-FORMERS

Read More
24 Aug, 2021

FORMULATION AND EVALUATION OF PRESS-COATED PULSATILE DELIVERY OF FLURBIPROFEN TABLETS

Read More
Impact Factor
8.01 (Year 2024)
UGC Approved
Journal no 47859

Join Our IPN

IJIRT Partner Network

Submit your research paper and those of your network (friends, colleagues, or peers) through your IPN account, and receive 800 INR for each paper that gets published.

Join Now

Latest Publication

Archive

View More

Recent Conferences

NCSEM 2024

National Conference on Sustainable Engineering and Management - 2024 Last Date: 15th March 2024

Submit inquiry