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@article{158616,
        author = {D.NAGAVALLI and P.NANTHAGOPAL},
        title = {Lenacapavir: An Overview’},
        journal = {International Journal of Innovative Research in Technology},
        year = {},
        volume = {9},
        number = {10},
        pages = {251-265},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=158616},
        abstract = {       Lenacapavir was approved for medical use in European Union in August-2022, Lenacapavir is the first of a new class of drugs called "Capsid inhibitors to be FDA-approved for treating HIV/AIDS. Lenacapavir a new type of antiretroviral medication for adult patients living with Human Immunodeficiency Virus type-1(HIV-1), who’s HIV Infections cannot be successfully treated with other available treatments due to resistance, intolerance considerations. Lenacapavir works by blocking the HIV-1 virus' protein shell (the Capsid) .Lenacapvir, in combination with other antiretroviral(s), is indicated for the treatment of multidrug-resistant human immunodeficiency virus type-1 (HIV-1)-Infection. Lenacapvir first formulation Oral Tablets and Subcutaneous injection-form at trade Name-(Sunlenac), Lenacapavir -is achieved in HIV RNA suppression .Lenacapvir is a long- acting, potent inhibitor of the HIV Capsid protein. Lenacapavir binds directly to HIV-capsid in a pocket between capsid protein subunits in hexamers.Treatement of emergent resistance to lenacapvir has been reported in the phase 2/3 CAPELLA trail evaluating Lenacapvir for HIV treatment. Combination antiretroviral therapy-suppression HIV-1 replication and increase CD 4+ cell counts. },
        keywords = {Lenacapavir, Capsid-Inhibitor, HIV-1, Anti-Retroviral agent, SUNLENCA.},
        month = {},
        }