Author Login IJIRT Partner Network (IPN) Login

Insilico or organ on chip in Pre-Clinical and Clinical Trials

  • Unique Paper ID: 158862
  • Volume: 9
  • Issue: 10
  • PageNo: 824-835
  • Abstract:
  • The organ-on-a-chip (OOAC) refers to a physiological organ biomimetic system built on a microfluidic chip. It involves biomaterial technology, cell biology and engineering combined together in a miniaturized platform. This reflects the structural and functional characteristics of human tissue and can predict response to an array of stimuli including drug responses and environmental effects. In this review, we introduce the concepts of OOAC and its application to the construction of physiological models, drug development, and toxicology from the perspective of different organs. We further discuss existing challenges and provide future perspectives for its application. These 'organs-on-chips' permit the study of human physiology in an organ-specific context, enable development of novel in vitro disease models, and could potentially serve as replacements for animals used in drug development and toxin testing.
Download article email to a friend

Cite This Article

  • ISSN: 2349-6002
  • Volume: 9
  • Issue: 10
  • PageNo: 824-835

Insilico or organ on chip in Pre-Clinical and Clinical Trials

Related Articles

Impact Factor
8.01 (Year 2024)
UGC Approved
Journal no 47859

Join Our IPN

IJIRT Partner Network

Submit your research paper and those of your network (friends, colleagues, or peers) through your IPN account, and receive 800 INR for each paper that gets published.

Join Now

Latest Publication

Archive

View More

Recent Conferences

NCSEM 2024

National Conference on Sustainable Engineering and Management - 2024 Last Date: 15th March 2024

Submit inquiry