HEPATO PROTECTIVE AND ANTIOXIDANT ACTIVITY OF AERVA LANATA AGAINST D-GALACTOSAMINE INDUCED OXIDATIVE STRESS IN RATS

HEPATO PROTECTIVE AND ANTIOXIDANT ACTIVITY OF AERVA LANATA AGAINST D-GALACTOSAMINE INDUCED OXIDATIVE STRESS IN RATS
Author(s):
S. Bhargavi, Sk. Abdul Saleem, D. Rathna Kumari, O. Mahendra varma, S.Ramesh, Y. Vyshnavi, J.N.Suresh Kumar
Keywords:
ABTS; DPPH; FRAP; antioxidant activity methods; Hepato protective; reducing power assay.
Abstract
Plants have a large number of bioactive compounds with high antioxidant activity. Studies for the determination of the Hepatoprotective and antioxidant activity of different plant species could contribute to revealing the value of these species as a source of new antioxidant compounds. There is a large variety of in vitro methods to quantify hepatoprotective and antioxidant activity, and it is important to select the proper method to determine which species have the highest antioxidant activity. Their extracts were analyzed using the following methods: 2,2-di-phenyl-1-picrylhydrazyl (DPPH) radical scavenging capacity assay, ferric reducing (FRAP) assay, Trolox equivalent antioxidant capacity (ABTS) assay, and reducing power (RP) assay. The four methods selected could quantify the antioxidant capacity(1). The Another difference established between these methods was the sensitivity obtained with each of them.
Article Details
Unique Paper ID: 160813 Publication Volume & Issue: Volume 10, Issue 1 Page(s): 1354 - 1361
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