Surwase Pratiksha, Dr. Tiwari shradhha, Shaikh Muskan, Kote Narayan, Dalal Pramod
Niosomes, Cholesterol, Composition, Application
When synthetic non-ionic surfactants are hydrated, either with or without the consolidation of cholesterol or other lipids, niosomes—non-ionic surfactant vesicles—form. They are vesicular structures, similar to liposomes, that can be used to transport both lipophilic and amphiphilic drugs. Being non-ionic, niosomes are a promising drug delivery system. These are biodegradable, biocompatible, and not immunogenic, thus show adaptability and flexibility in their structural characterization. For the treatment of tumors, viral infections, and other microbial illnesses, niosomes have generally been evaluated for controlled discharge and targeted delivery. Both hydrophilic and lipophilic drugs can become entangled by niosomes, which increases the drug residence time in the blood circulation. Medication encapsulation in vesicles is expected to prolong the presence of the medication in the systemic circulation, improve penetration into target tissue, and possibly reduce toxicity if targeted take-up is successful. This review focuses on the various components of niosomes, their different types, their advantages, methods of preparation, factors affecting, characterizations, and applications.
Article Details
Unique Paper ID: 160911

Publication Volume & Issue: Volume 10, Issue 2

Page(s): 316 - 329
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