A review on Parkinson’s disease
Author(s):
Pournima Krishnadatta Sutar , Roshani Arjun Kumbhar, Patil Rajvardhan Dipak, Mulla Simran Aslam, Mehta Kruti Chetan , Vidya Namdeo Dange, Swapnil Santosh Mali
Keywords:
Neurodegenerative disorder, Movement disorder , Dopaminergic medication, Deep brain stimulation, Levodopa.
Abstract
In neurological practice, Parkinson's disease is a prevalent movement illness that can be difficult to diagnose and treat. Considering that PD patients have a wide range of motor and non-motor symptoms, the diagnosis is clinical and occasionally challenging.Parkinson's disease (PD) is a progressive neurodegenerative condition primarily brought on by a brain dopamine deficiency. Dopaminergic cell death causes a reduction in dopamine levels in Parkinson's disease (PD) brain tissue. Dopamine is a neurotransmitter involved in motivation, movement, memory, and other processes. In the brains of PD patients, dopamine depletion contributes to motor inadequacy and may also be the source of the cognitive impairment seen in certain PD patients.The hallmark motor symptoms of Parkinson's disease include bradykinesia (slowness of movement), resting tremors, rigidity, and postural instability. These symptoms can significantly impair a person's ability to perform daily activities and lead to a decreased quality of life. Non-motor symptoms, such as depression, anxiety, cognitive impairment, and autonomic dysfunction, are also common and can further complicate the management of the disease. Diagnosis of Parkinson's disease is primarily based on clinical assessment and the presence of characteristic motor symptoms. There are no definitive laboratory tests to confirm the disease, although neuroimaging techniques such as MRI and DaTscan can help rule out other conditions with similar symptoms.
Article Details
Unique Paper ID: 161798

Publication Volume & Issue: Volume 10, Issue 6

Page(s): 201 - 207
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