A Review on Mucoadhesive drug delivery system

A Review on Mucoadhesive drug delivery system
Author(s):
Akshada Baburao falle, Shraddha shivaji hajare
Keywords:
Mucoadhesive, Mucoadhesion, Metabolism and Polymer
Abstract
Mucoadhesive drug delivery systems lengthen the dosage form's residence time at the site of absorption by interacting with mucin molecules and the mucus layer that covers the mucosal epithelial surface. The phenomena of interfacial molecular attractive forces in the layer of surface of a biological membrane and the natural or synthetic polymer, which permits the polymer to cling to the membrane's surface for an extended amount of time, is known as mucoadhesion. The mucoadhesive buccal drug delivery system has numerous benefits that make it a unique drug delivery method for both local and systemic administration of different medications. The primary benefit of using this route for drug administration is that it avoids the first pass metabolism of many medications, which are subject to their first pass metabolism in the liver.
Article Details
Unique Paper ID: 162187 Publication Volume & Issue: Volume 10, Issue 8 Page(s): 197 - 206
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