Author Login IJIRT Partner Network (IPN) Login

A REVIEW ARTICLE ON THE CHEMICAL STRUCTURE AND MECHANISM OF COLCHICINE

  • Unique Paper ID: 162809
  • Volume: 10
  • Issue: 11
  • PageNo: 1465-1467
  • Abstract:
  • From ancient times Colchicine has been used for therapeutic purposes and relatively safe anti-inflammatory drug traditionally used in gout and over the last 50 years in familial Mediterranean fever. Colchicine is an alkaloid extracted from the colchicum autumnale plant, having molecular formula C22H25NO6 consisting of three rings. It seems efficacious in the treatment of acute pericarditis and prevention of recurrence, Many researchers are concerned that structural changes will increase their therapeutic effectiveness and reduce toxicity arising from it. In patients suffering from statins and antiplatelet agents following acute coronary syndromes or stable coronary disease, adding low-dose colchicine achieved secondary prevention of major cardiovascular events (myocardial infarction, stroke, or cardiovascular death) with risk reduction up to 0.75. This may also be useful in Behcet's syndrome and most recently, in improving outcomes of COVID-19 infection. The pharmacological effectiveness of colchicine against Gout, Familial Mediterranean Fever, and many other diseases.
Download article email to a friend

Cite This Article

  • ISSN: 2349-6002
  • Volume: 10
  • Issue: 11
  • PageNo: 1465-1467

A REVIEW ARTICLE ON THE CHEMICAL STRUCTURE AND MECHANISM OF COLCHICINE

Related Articles

Impact Factor
8.01 (Year 2024)
UGC Approved
Journal no 47859

Join Our IPN

IJIRT Partner Network

Submit your research paper and those of your network (friends, colleagues, or peers) through your IPN account, and receive 800 INR for each paper that gets published.

Join Now

Latest Publication

Archive

View More

Recent Conferences

NCSEM 2024

National Conference on Sustainable Engineering and Management - 2024 Last Date: 15th March 2024

Submit inquiry