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FORMULATION AND EVALUATION OF TRANSDERMAL PATCH FOR ARTHRITIS

  • Unique Paper ID: 163579
  • Volume: 10
  • Issue: 11
  • PageNo: 1791-1796
  • Abstract:
  • The formation of Celecoxib Transdermal patch to avoid first pass metabolism and to overcome the problems associated with its biological short half-life and fluctuations in plasma concentration upon oral administration. The patch was prepared using Solvent Casting Method, using HPMC as polymer, Ethanol: distilled water as solvent. The physical evaluation of the prepared patch include Organoleptic observation, moisture uptake, moisture loss, content uniformity test, stability studies, swelling index, folding endurance. The drug release was determined using Franz diffusion cells in phosphate buffer (pH 7.4).
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Cite This Article

  • ISSN: 2349-6002
  • Volume: 10
  • Issue: 11
  • PageNo: 1791-1796

FORMULATION AND EVALUATION OF TRANSDERMAL PATCH FOR ARTHRITIS

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Impact Factor
8.01 (Year 2024)
UGC Approved
Journal no 47859

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