FORMULATION AND EVALUATION OF TRANSDERMAL PATCH FOR ARTHRITIS

  • Unique Paper ID: 163579
  • Volume: 10
  • Issue: 11
  • PageNo: 1791-1796
  • Abstract:
  • The formation of Celecoxib Transdermal patch to avoid first pass metabolism and to overcome the problems associated with its biological short half-life and fluctuations in plasma concentration upon oral administration. The patch was prepared using Solvent Casting Method, using HPMC as polymer, Ethanol: distilled water as solvent. The physical evaluation of the prepared patch include Organoleptic observation, moisture uptake, moisture loss, content uniformity test, stability studies, swelling index, folding endurance. The drug release was determined using Franz diffusion cells in phosphate buffer (pH 7.4).

Copyright & License

Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{163579,
        author = {Manish Swarnkar and DR. HARISH SHARMA and GYANESH KUMAR SAHU, YOGESH CHANDRA and KHUSHI SHARMA, SURESH KUMAR and DEEPIKA CHANDRA and CHANDRAPRABHA SAHU and RAJESH KUMAR NEMA and PRERANA SAHU},
        title = {FORMULATION AND EVALUATION OF TRANSDERMAL PATCH FOR ARTHRITIS },
        journal = {International Journal of Innovative Research in Technology},
        year = {},
        volume = {10},
        number = {11},
        pages = {1791-1796},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=163579},
        abstract = {The formation of Celecoxib Transdermal patch to avoid first pass metabolism and to overcome the problems associated with its biological short half-life and fluctuations in plasma concentration upon oral administration. The patch was prepared using Solvent Casting Method, using HPMC as polymer, Ethanol: distilled water as solvent. The physical evaluation of the prepared patch include Organoleptic observation, moisture uptake, moisture loss, content uniformity test, stability studies, swelling index, folding endurance. The drug release was determined using Franz diffusion cells in phosphate buffer (pH 7.4).},
        keywords = {Celecoxib , Transdermal patch and conventional dosage form},
        month = {},
        }

Cite This Article

  • ISSN: 2349-6002
  • Volume: 10
  • Issue: 11
  • PageNo: 1791-1796

FORMULATION AND EVALUATION OF TRANSDERMAL PATCH FOR ARTHRITIS

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