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Stem Cell-Derived Therapies for Tissue Repair and Regeneration

  • Unique Paper ID: 166459
  • Volume: 11
  • Issue: 2
  • PageNo: 957-969
  • Abstract:
  • Stem cell-based regenerative medicine holds immense promise for addressing organ shortages, chronic diseases, and tissue regeneration. Stem cell research has evolved significantly since Maximow's discovery of hematopoiesis in 1902, culminating in transformative breakthroughs such as the development of induced pluripotent stem cells (iPSCs) by Yamanaka in 2006 and the application of mesenchymal stem cells (MSCs) in COVID-19 treatment in 2020-2021. This article explores the historical milestones, clinical applications, emerging technologies, and future prospects of stem cell research. From the transplantation of cardiac and blood vessel cells for cardiac regeneration to the development of neuronal tissue engineering through electrical stimulation, the potential of stem cell-based therapies in treating various animal diseases, including heart failure, spinal cord injury, and neurodegenerative diseases, is elucidated. Additionally, the role of MSCs in improving local microenvironments for stress urinary incontinence treatment and managing inflammatory diseases through their immunomodulatory properties is examined. This comprehensive review highlights the transformative impact of stem cell research on regenerative medicine and underscores the need for continued innovation in addressing the challenges and limitations of stem cell-based therapies.
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Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 2
  • PageNo: 957-969

Stem Cell-Derived Therapies for Tissue Repair and Regeneration

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Journal no 47859

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