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A Review: Solid Lipid Nanoparticles

  • Unique Paper ID: 166862
  • Volume: 11
  • Issue: 2
  • PageNo: 2720-2729
  • Abstract:
  • Solid lipid nanoparticles (SLNs) have emerged as promising carriers for poorly water-soluble drugs and cosmetic active ingredients. This review provides an extensive overview of SLNs, including their introduction, advantages, disadvantages, aims, methods of preparation, characterization techniques, and routes of administration. SLNs offer several advantages, such as controlled drug release, increased drug stability, high drug payload, and versatility in administration routes. Various preparation methods, including high-pressure homogenization, ultrasonication, solvent evaporation, and others, highlight the flexibility in production techniques. Characterization methods ensure quality control and provide insights into particle size, distribution, crystallinity, and surface properties. Furthermore, SLNs exhibit promising applications in pharmaceuticals, cosmeceuticals, vaccine delivery, agriculture, and targeted drug delivery for cancer treatment. Their ability to enhance drug bioavailability, reduce side effects, and provide sustained release makes them attractive for diverse therapeutic needs. Despite their advantages, SLNs have limitations such as limited drug loading capacity and potential particle growth. However, ongoing research aims to overcome these challenges and further optimize SLNs for clinical applications. In conclusion, SLNs represent a versatile and promising drug delivery system with potential applications across various fields. Continued research and development efforts are necessary to fully harness the benefits of SLNs and address existing limitations, ultimately advancing drug delivery technology and improving patient outcomes.
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Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 2
  • PageNo: 2720-2729

A Review: Solid Lipid Nanoparticles

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