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Bioinspired Nanocarriers: The Future of Targeted Cancer Treatment – An Overview

  • Unique Paper ID: 167976
  • Volume: 11
  • Issue: 4
  • PageNo: 1010-1020
  • Abstract:
  • Cancer is the second-leading cause of death in the world, and the survey conducted by the World Health Organization (WHO) says that cancer is the first and second-leading cause of death in 183 countries. The initial diagnosis of cancer can significantly improve patient survival. Conventional cancer therapies like surgery, radiotherapy, and chemotherapy have so many hurdles, including a lack of specificity and the formation of drug resistance. Nanoparticles (NPs) can be the solution to all the problems. NPs can be designed for targeted drug delivery and improve the solubility, stability, and half-life of anti-cancer drugs. Biomimetic nanoparticles (NPs) can mimic the action of the biological material, which improves biocompatibility and reduces the immune attack. These include cell membrane-coated nanoparticles (NPs) and natural protein-based nanoparticles (NPs). For example, RBC membrane-coated NPs can escape detection by the immune system, stay in the blood stream for a longer duration, and deliver the anti-cancer drug to the tumor site. Similarly, WBC membrane-coated NPs can naturally interact with the immune system for drug delivery and help with treatment by activating the immune system to fight against cancer. Even more, cancer cell membrane-coated NPs and albumin-based NPs have unique advantages for targeted drug delivery and the treatment of cancer. Further research on the biomimetic NPs shows their one more unique ability to cross the blood-brain barrier (BBB) and is essential for targeted drug delivery for brain diseases.
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Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 4
  • PageNo: 1010-1020

Bioinspired Nanocarriers: The Future of Targeted Cancer Treatment – An Overview

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