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Effects of Hyperglycemia on Electrolyte Indices in Type 2 Diabetes Mellitus

  • Unique Paper ID: 168084
  • Volume: 11
  • Issue: 4
  • PageNo: 1520-1523
  • Abstract:
  • Background: Type 2 Diabetes Mellitus (T2DM) is primarily characterized by insulin resistance and relative insulin deficiency. While the endocrine dysfunction of the pancreas in T2DM (type 2 diabetes mellitus) is well-documented, emerging evidence suggests that pancreatic exocrine functions are also significantly impacted. Electrolyte imbalance is commonly present in patients with type-2 diabetes mellitus. Introduction: Due to hyperglycemia plasma osmolality and impaired renal function is rise which contributing to a change in electrolyte levels. Diabetic patients are more likely develop electrolytes imbalance then control or healthy patients. Material and Methods: In this hospital based study120 subjects between the healthy and diabetic patients. The electrolyte profile was assessed using standard methodologies. Statistical analysis was performed using the GraphPad Prism9 stat® Software. Analysis of data was done using one-way ANOVA employing Tukey’s test, after analysis. p<0.05 was found to be statistically significant. Results: In our study population Phosphate was seen higher in diabetic patients as compared with all electrolyte parameters except magnesium which was observed normal with healthy patients. Rest of the parameters like calcium, chloride, sodium and potassium were observed difference in their level (p < 0.005) as compared with the healthy patients. Conclusion: Therefore, it can be concluded that diabetes mellitus also be responsible for the imbalance of electrolytes in the body. High phosphate level and low magnesium level might be associated with the insulin resistance. Low sodium level might be dehydration of cells and low calcium might be due to low calcium absorption in the diabetes mellitus
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  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 4
  • PageNo: 1520-1523

Effects of Hyperglycemia on Electrolyte Indices in Type 2 Diabetes Mellitus

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