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Silica supported Boric acid catalyzed green methodology for the synthesis of substituted Pyrazole Curcumin analogues

  • Unique Paper ID: 171235
  • Volume: 11
  • Issue: 7
  • PageNo: 3045-3048
  • Abstract:
  • Curcumin is naturally occurring yellow pigments isolated from Curcuma longa, structurally it is polyphenolic compound consisting spectacular biological activity. However, clinical utility of curcumin is limited due to its poor bioavailability. Synthesis of heterocyclic curcumin analogues is major attempt to overcome such limitations. Present study reveals the silica-boric acid (SiO2-H3BO3) as an efficient catalyst for the preparation of pyrazole Curcumin derivatives. Propose method offers rapid one step synthesis of product with desire green profile. In summary, present methodology offers rapid synthesis of pyrazole analogues of curcumin in short course of time with many advantages like environmentally benign catalyst and solvent, cost effective, easy product separation and clean reaction profile
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Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 7
  • PageNo: 3045-3048

Silica supported Boric acid catalyzed green methodology for the synthesis of substituted Pyrazole Curcumin analogues

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Impact Factor
8.01 (Year 2024)
UGC Approved
Journal no 47859

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