Synthesis and Application of C-5'-triazolyl-nucleosides

  • Unique Paper ID: 172494
  • Volume: 11
  • Issue: 9
  • PageNo: 861-868
  • Abstract:
  • Modified nucleosides are the core precursor nucleic acid, and it has a significant contribution medicinal chemistry and drug discovery. So that, prepare different triazolyl scaffolds, ruthenium and copper catalysed azide-alkyne 1,3-dipolar cycloaddition reactions also known as click reaction have developed as a facile and efficient unique tool because of its simplicity and ideal conditions. Introduction of a triazole ring in nucleosides, improves their therapeutic value and different photophysical attributes. In this article, discussed the synthesis and application of C-5’-triazolyl nucleosides.

Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 9
  • PageNo: 861-868

Synthesis and Application of C-5'-triazolyl-nucleosides

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